| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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Levofloxacin (Levofloxacin) is the levofloxacin isomer, water soluble is 8 times more than ofloxacin, easier to make injection, less toxic side effects, was first marketed in Japan in 1994, belongs to the third generation of quinolone antibacterial drugs. The antibacterial effect is mainly exerted by the inhibition of DNA replication, transcription, repair and recombination of the topoisomerase and DNA rotation enzyme (Topoisomerase). Levofloxacin was twice as active as Levofloxacin against most clinical isolates. Because of its good activity against Streptococcus pneumoniae, Haemophilus influenzae and Mycoplasma pneumoniae, it is also called &ldquo. Respiratory quinolones ” And had stronger antibacterial activity against Pseudomonas aeruginosa than the former.
It has been widely used in clinic because of its advantages of broad antibacterial spectrum, strong antibacterial action and no need to do skin sensitive test. However, long-term clinical practice has shown that Levofloxacin can cause a wide range of adverse reactions (ADRs). In the 2016 Annual Report on Adverse Drug Reaction Monitoring, anti-infective drugs ranked first, and Levofloxacin ranked first among anti-infective drugs. Therefore, its clinical use is also limited.
Synonym
(s)-ofloxacin;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid,9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-,(S)-;Cravit;HR355;LeChemicalbookvaquin;RWJ25213-097;Tavanic;(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylicacid
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| Product Name: | Levofloxacin | CAS NO.: | 100986-85-4 |
| Molecular weight: | 361.37 | EINECS: | 600-146-0 |
| Formula: | C18H20FN3O4 | Melting point: | 218°C |
| Density: | 1.48±0.1 g/cm3 | Boilting point: | 572ºC |
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Function
Levofloxacin has strong antibacterial activity against most Enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella, Proteus, Shigella, Salmonella and Haemophilus influenzae, Legionella pneumophila, Neisseria gonorrhoeae and other G-bacteria. It also has antibacterial effect on G+ bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, mycoplasma pneumoniae and Chlamydia pneumoniae, but it has poor effect on anaerobic bacteria and enterococcus. Levofloxacin, moxifloxacin and Jimifloxacin enhance their effects on G+ bacteria such as Streptococcus pneumoniae and Streptococcus pyogenes, and pathogenic microorganisms of community-acquired respiratory tract infection such as mycoplasma pneumoniae, chlamydia pneumoniae and Legionella pneumophila, so they are also known as "respiratory quinolones".
Application
Levofloxacin is mainly used for mild and moderate infection caused by sensitive bacteria. The dosage is 250mg to 500mg each time, once a day. Its corresponding indications are very broad, including but not limited to: community-acquired pneumonia;
Bacterial sinusitis; Acute bronchitis; Complex and uncomplicated skin tissue or skin structural infection; Chronic bacterial prostatitis; Complex urinary tract infection
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Xi'an Haoze Biotechnology Co., Ltd. established in 2015, is a professional engaged in the research, development, sale, and service of Turkesterone, NMN, Astaxanthin, Curcumin, Coenzyme Q10.We are located in Xi'an with convenient transportation access. we have excellent teams who focus on product development & design, quality control & inspection, and company running. Dedicated to strict quality control and thoughtful customer service, our experienced staff members are always available to discuss your requirements and ensure full customer satisfaction. In addition, we have obtained ISO9001,HALAL and Kosher certificates. Selling well in all cities and provinces around China, our products are also exported to clients in such countries and regions as North America, Europe, Oceania, and the Middle East. If you have any new ideas or concepts for the products, please contact us. We are glad to work together with you and finally bring you the satisfied products.We also welcome OEM and ODM orders. Whether selecting a current product from our catalog or seeking engineering assistance for your application, you can talk to our customer service center about your sourcing requirements."Top Quality, Customer First" is our adhering, to and implementing the principle of "high standards, safe & fast delivery, good service", to create a mutual benefit partnership with customers. We warmly welcome customers from at home and abroad to establish cooperation and create a bright future with us together.
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