Customization: | Available |
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Application: | Antineoplastic Drugs |
Grade: | Pharmecutical Grade |
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Irinotecan is a semi-synthetic water-soluble camptothecin derivative. This product and its metabolite SN38 are inhibitors of DNA topoisomerase I. The complex formed with topoisomerase I and DNA can cause DNA single-strand breaks, prevent DNA replication and inhibit RNA synthesis, which is the S phase of the cell cycle. Specificity.
Synonym
Irinotecan(freeBase);Irinotecan(TECANS);1,4'-Bipiperidine-1'-carboxylicacid(S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester;DQ-2805;(4S)-4,11-Diethyl-4-hydroxy-9-[[(4-piperidinopiperidino)carbonyl]oxy]-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione;SN-38Chemicalbook-11;(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl4-(piperidin-1-yl)piperidine-1-carboxylate;[1,4'-Bipiperidine]-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester,(S)-
Product Name: | Irinotecan | CAS NO.: | 97682-44-5 |
Appearance: | Light yellow powder | EINECS: | 691-567-9 |
Formula: | C33H38N4O6 | Melting Point: | 222-223ºC |
Boiling Point: | 873.4±65.0 ºC | Density: | 1.40±0.1 g/cm3 |
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Function of Matrine
Large-scale clinical trials have shown that irinotecan hydrochloride has significant inhibitory effects on a variety of tumors such as colon cancer, small cell lung cancer, rectal cancer, leukemia, etc., and is still effective against fluorouracil-resistant cases. Therefore, irinotecan hydrochloride has attracted widespread attention around the world.
Application
It is a first-line drug for advanced colorectal cancer and can also be used for postoperative adjuvant chemotherapy; it also has certain effects on lung cancer, breast cancer, pancreatic cancer, etc.
Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.0% |
β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 99.0% |
Olivetol(3,5-hydroxypentylbenzene) | 500-66-3 | 99.0% |
Compound 7P | 1890208-58-8 | 98.0% |
Noopept,GVS-111 | 157115-85-0 | 99.5% |
Piracetam | 7491-74-9 | 99.0% |
Aniracetam | 72432-10-1 | 99.0% |
Nefiracetam | 77191-36-7 | 99.0% |
Pramiracetam | 68497-62-1 | 99.0% |
Fasoracetam | 110958-19-5 | 99.0% |
Sunifiram | 314728-85-3 | 99.5% |
Coluracetam | 135463-81-9 | 99.0% |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99.0% |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50.0% |
Citicoline | 987-78-0 | 99.0% |
Galantamine Hydrobromide | 69353-21-5 | 98.0% |
PRL-8-53 | 51352-87-5 | 99.0% |
NSI-189 Phosphate | 1270138-41-4 | 99.0% |
NSI-189 | 1270138-40-3 | 99.0% |
Tianeptine | 66981-73-5 | 99.0% |
Tianeptine sodium | 30123-17-2 | 99.0% |
Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
Agomelatine | 138112-76-2 | 99.0% |
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