Customization: | Available |
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Function: | Skin Whiten |
Certification: | GMP, ISO, HACCP, QS, KOSHER, NOP, JAS, ISO22000, Halal |
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Melanotan II is a synthetic melanocortin peptide analog that exhibits thermogenic, anti-inflammatory, and anti-atherosclerotic activities; it non-selectively binds melanocortin receptors. Melanotan II was originally designed to promote skin pigmentation, but has since been shown to induce arousal and increase body temperature in clinical settings and animal models. Melanotan II also decreases fluorodeoxyglucose uptake in atherosclerotic plaques, decreases pro-inflammatory cytokine levels, and increases aortic vasorelaxation in animal models of atherosclerosis.
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Item | Specification |
Appearance | white crystalline powder |
Determination | ≥99% |
Heavy metal | ≤10ppm |
Arsenic | ≤1ppm |
Lead | ≤3ppm |
Merc ury | ≤0.1ppm |
Cadmium | ≤1ppm |
Total plates | ≤1000cfu/g |
Yeast and mold | ≤100cfu/g |
E. coli | negative |
Salmonella | negative |
Conclusion | The product complies with the standard. |
Function
1. Melanotan 2 powder is a synthetic receptor agonist for melanocortin.
2. It is an injectable peptide hormone that promotes tanning.
Melanotan (MT)-II is a potent non-selective melanocortin receptor agonist with high affinity for MC1,MC3,MC4,and mc5 receptor subtypes which are involved in the regulation of a number of physiological systems such as the pigmentary system,energy homoeostasis, sexual functioning, the immune system, inflammation, and the cardiovascular system.
Melanotan(MT)-IIexerts a dose-dependent inducer activity on erection by eliciting erectile events and shortening latency of the first erectile event to occur. Erectile responses elicited by cavernous nerve stimulation are increased after i.v.melanotan (MT) -II(1mg/kg), thereby exerting facilitator effect on erection. Melanotan(MT)-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Melanotan(MT)-II significantly enhances the recovery of sensory function following a crush lesion of the sciatic nerve in the rat at a dose of 20μg/kg per 48h,s.c., but not at a dose of 2 or 50μg/kg. Melanotan(MT)-II is a potent initiator of penile erection in men with erectile dysfunction. Melanotan(MT)-II reduces food intake and body weight and invokes thermogenic responses in a mouse model.
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