Pharmaceutical Intermediate Raw Material 99% Tropicamide Powder CAS 1508-75-4 Tropicamide

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: HZ-Tropicamide
• Grade: Healethcare Products
• CAS No.: 1508-75-4
• Appearance: White Crystal Powder
• Molecular Formula: C17h20n2o2
• Assay: 99%
• Test Method: HPLC
• Molrcular Weight: 284.35
• Application: Pharmaceutical Grade
• Shelf Life: 2 Years
• OEM: Customization Label and Packing Bottles
• Transport Package: Bottle and Carton
• Specification: 500mg/capsule
• Trademark: Customzied
• Origin: China
• HS Code: 29333990
• Production Capacity: 5000kg/Month

Product Description

Product Description

Topicumide is an anticholinergic drug, white crystalline powder at room temperature, odorless, slightly soluble in water, soluble in ethanol, dilute hydro chloric acid, dilute sulfuric acid and chlor oform, can block acetylcholine caused by iris sphincter and ciliary muscle excitability. Its 0.5% solution can cause mydriasis; 1% solution can cause cycloplegia and mydriasis. Clinically, it is mainly used for the treatment of eye drops, mydriasis and regulatory paralysis.

 

Product Specificaiton

Product Name:	Tropicamide	Assay:	99%
Standard	Enterprise standard	Appearance:	White Crystalline Powder
CAS NO	1508-75-4	EINECS	216-140-2
Minimum  order  quantity	500g	Packing:	1kg/aluminum foil bag; 25kg/drum

Items	Requirements	Results
Appearance	White to off white powder	White powder
Solubility	Practically insoluble in water, soluble in dimethylformamide,  slightly soluble in ethanol(96%)	Confirms
Identification	A. M.P. 244~248ºC	244.5~245.5ºC
	B. IR should comply	Confirms
	C. TLC should comply	Confirms
	D. It gives the reaction of non-nitrogen substituted barbiturates.	Confirms
Clarity of solution	The solution is clear and not more intensely colored than  reference solution Y6	Confirms
Related substance	Total impurities≤0.5%	≤0.29%
	Individual impurity≤0.25%	≤0.18%
Loss on drying	≤0.5%	0.07%
Sulphated ash	≤0.1%	≤0.05%
Heavy metal	≤20ppm	<20ppm
Assay	99.0%~101.0%	99.49%
Conclusion: This product conforms to the EP7.0 detection.

 

Function & Application

Function:
Tropicamide is an anticholinergic drug that can block the excitatory effect of iris sphincter and ciliary muscle caused by acetylcholine. Clinically, it is mainly used to treat mydriasis and accommodative paralysis.
Application:
Topicarmide is a synthetic derivative of tropic acid. It has a low dissociation constant, good intraocular permeability, and strong tissue diffusion, which may be the reason for its rapid onset and short maintenance time. The mydriatic and regulatory paralysis effect of this product reaches a peak within 20-30 minutes after eye drops of 0.5% and 1% solution. Subsequently, the effect gradually decreases, and the paralysis (residual) is regulated for 2~6 hours. Mydriasis (residual) for about 7 hours. Topiracamide is an atropine-like drug, which can sharply increase the intraocular pressure of angle-closure glaucoma and may also stimulate undiagnosed angle-closure glaucoma. The intensity of cyclomodulatory paralysis of topiramide eye drops is closely related to the dose, and its four concentrations, 0.25%, 0.5%, 0.75% and 1%, have regulatory paralytic effects. After eye drops, the maximum residual adjustment degree was 0.25% 3.17 diopter and 1% 1.30 diopter, respectively. If the residual adjustment degree can be maintained at or below 2.0 diopters, 0.75% and 1% solutions can be maintained for 40 minutes, and 0.5% can be maintained for about 15 minutes. After a drop of 1% solution to the eye, the second drop can obtain a more satisfactory cycloplegic effect of about 20~30 minutes. After 2~6 hours, I can read books and newspapers, and the adjustment function will return to the level before drops within 6 hours.

OEM Service

As a professional health product supplier, we can customize Topicarmide powder with different packing, Topicarmide capusel with different bottles according to your formula and requests.

                                                                   

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Packaging & Shipping

Goods weight	Packing	Shipping method	Lead-time
1-50kg	Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum	International express	1~3 days after your payment
100-200kg	25kg/drum,use two layer PP bag,then into cardboard drum	Air shipping Sea Shipping	3~5 days after your payment
Over 500kg	25kg/drum,use two layer PP bag,then into cardboard drum	Sea shipping	5~10 days after your payment

 

Company Profile

FAQ

Q1: Can I get some free sample?
A: Yes, we offer free sample to client and you only need to pay the fright.

Q2: Could you accept customzied order? 
A: Yes, we accept customized service according your requests, you can communicate with sales manager to know more details.

Q3: When the product can be delivery? 
A: We normal delivery the product within 2-4 days, the more details will inform to you by our sales manager. 

Q4: Could i get certificate of analysis (COA) about product?
A: Of course, please contact us to get it. 
 

Q5: Is there any discount?

A:Yes, we can give you discount, but it depends on your quantity.