• Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
  • Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
  • Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
  • Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
  • Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
  • Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP, Halal
Suitable for: Adult
State: Powder
Purity: >99%
Samples:
US$ 50/Gram 1 Gram(Min.Order)
| Request Sample
Customization:
Diamond Member Since 2023

Suppliers with verified business licenses

Shaanxi, China
Experienced Team
The supplier has 13 foreign trading staff(s) and 4 staff(s) with over 6 years of overseas trading experience
In-stock Capacity
The supplier has In-stock capacity
Fast Delivery
The supplier can deliver the goods within 15 days
ODM Services
The supplier provides ODM services
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  • Overview
  • Product Description
  • Specification
  • Functions&Application
  • Our OEM
  • Packaging & Shipping
  • Company Profile
  • Certifications
  • FAQ
Overview

Basic Info.

Model NO.
HZ-Isotretinoic acid
Name
Isotretinoic Acid Powder
Grade
Pharmaceutical Intermediate API
Samples
Avaliable
Packing
According to Customer Requirements
MOQ
2kg
Certificates
Halal, ISO, Kosher
Package
Foil Bag and Drum and Carton
Shelf Life
2 Years
Test Method
HPLC
MW
300.44
Application
Pharmaceutical Intermediate
Function
Cosmetic Material API Isotretinoic Acid 99%
CAS
4759-48-2
Molecular Formula
C20h28o2
Density
1.011 g/cm3
Transport Package
25kg/Drums or Carton, 1kg or Less/Bag
Specification
99%
Trademark
HAOZE
Origin
Shaanxi
Production Capacity
750kg/Month

Product Description

Product Description

High Quality Isotretinoic acid Powder

lsoretinoic acid belongs to the first generation of vitamin A acids. It is a stereoisomer of all trans vitamin A acid. Oral administration has an anti oil effect and has a special effect on severe acne. It has a strong and rapid function of inhibiting the proliferation and differentiation process of skin gland cells. Clinically used for severe acne, cystic acne, and aggregated acne that are ineffective in the treatment of other drugs.

Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Isoretinoic acid is a type of retinol derivative used in acne treatment products, with improved bioavailability and percutaneous absorption. The appearance is yellow orange crystalline powder. Currently, research is being conducted on the combination of photoaging skin treatment.

Specification

HAOZE Supply Top Grade Isoretinoic Powder

Sample Order is supported.  MOQ is 1kg. 

Extra OEM services are:  Package/Private Label /Formula customization 

Product Name: Isoretinoic Assay:  99% 
Standard Enterprise standard Appearance: Yellow orange crystalline powder
CAS NO 4759-48-2 MF C20H28O2
MW 300.44g/mol EINECS 225-296-0
Minimum  order  quantity 1kg Packing: 1kg/aluminum foil bag; 25kg/drum
 
Items Standards Results
Physical Analysis
Description light yellow Powder Complies
Assay 99% 99.12%
Mesh Size 100 % pass 80 mesh Complies
Ash ≤ 5.0% 2.85%
Loss on Drying ≤ 5.0% 2.85%
Chemical Analysis
Heavy Metal ≤ 10.0 mg/kg Complies
Pb ≤ 2.0 mg/kg Complies
As ≤ 1.0 mg/kg Complies
Hg ≤ 0.1 mg/kg Complies
Microbiological Analysis
Residue of Pesticide Negative Negative
Total Plate Count ≤ 1000cfu/g Complies
Yeast&Mold ≤ 100cfu/g Complies
E.coil Negative Negative
Salmonella Negative Negative
Storage: Stockpiled at the ventilated place, avoiding rain, moisture and insolation. Please handle with care to prevent bag damage, store away from toxic substances.
Packing: 25kg /bag.
Loading: 18MT/20FCL
Shelf Life: Two years when properly stored.

Functions&Application

1. It can reduce sebaceous gland and inhibit the activity of sebaceous gland, reducing the effect of secretion of the sebaceous glands, thus inhibiting the growth of Propionibacterium which relies on lipid environment.

2. It has an anti-keratosis effect, can inhibit the excess proliferation of epidermal and promote its differentiation. It also reduces the keratosis of hair follicles and the catheter of sebaceous glands.

3. It can also affect the function of lymphocytes and monocytes, and inhibit the chemotaxis of neutrophil, and thus having anti-inflammatory activity.

4. It can exert its therapeutic effect by selectively binding Vitamin A acid nuclear receptors. It can inhibit the proliferation of acne rod bacilli. Moreover it has effects of immunity stimulation at low doses, but has immunity suppression effect at high doses.

5. It can inhibit the biogenesis of collagenase and gelatinase in the skin, and can also inhibit the activity of ornithine decarboxylase. Owing to the major role of ornithine decarboxylase in inducing skin mutations, so
Isoretinoic can also suppress tumorigenesis.

6. When subjects to topical administration, it has a similar mechanism of action as vitamin A acid which induces the proliferation of epidermal cell, promotes the differentiation of epidermal cell granular layer into the stratum corneum. It can also regulate the horny plug occurring during some abnormal cornification processes of Hair follicle sebaceous epithelium, and thus playing a therapeutic role.

Our OEM

We also supply various other pharmaceutical raw materials. Perhaps there are still many that are not reflected in the table below. But no matter what product you want, you can contact us directly.

Product Name CAS No. Product Name CAS No.
Lufenuron 103055-07-8 Toltrazuril 69004-03-1
Nitenpyram 120738-89-8 Praziquantel/Biltricide 55268-74-1
Fenbendazole 43210-67-9 Tetramisole Hcl 5086-74-8
Levamisole 14769-73-4 Ponazuril 9004-4-2
Diclazuril 101831-37-2 Florfenicol 73231-34-2
Albendazole 54965-21-8 Mebendazole 31431-39-7
Ivermectin 70288-86-7 Enrofloxacin Hcl 112732-17-9
 
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
 
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Packaging & Shipping

We accept International Express--Fedex/DHL/UPS, air shipping and sea shipping

1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag inside and paper carton outside ) or as per your request.
25kg/drum (25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside. Drum Size: 510mm high, 350mm diameter) ;
Storage: Storein cool & dry place. Do not freeze. Keep away from strong light and heat.
Shelf life: two years when properly stored.
Shipping method: International express by air, by sea, UPS and EMS service.

Cargo weight
 
Packing
 
Shipping method
 
Lead-time
 
1-50kg
 
Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum
 
International express
 
1~3 days after your payment
100-200kg
 
25kg/drum,use two layer PP bag,then into cardboard drum
 
Air shipping
Sea Shipping
3~5 days after your payment
Over 500kg
 
25kg/drum,use two layer PP bag,then into cardboard drum
 
Sea shipping
 
5~10 days after your payment
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Company Profile

Xi'an Haoze Biotechnology Co., Ltd. Established in 2014, is a professional company engaged in the research, development, sales of health care material, cosmetics material and food additive ingredients. We are located in Xi'an City in the middle of China, which is back to Qinling Mountain, have a huge natural resources with convenient transportation.

We have excellent team who focus on product development & design, quality control & inspection, and company running. Dedicated to strict quality control and thoughtful customer service. There is a whole production line with extracting, column chromatography, reaction still, spray dry, freeze dry and vacuums dry equipment, it could produce 350kg finished product per hour, the annual production capacity is 2500-3000 tons. Also we have a full-scale of testing facility which are UV, HPLC, TLC and others. We own a GMP medical clean room which cover an area of 2000m2, and have research project with our local collage or institution every year. In addition, we have obtained ISO22000, HALAL and Kosher certificates to support different customer's request. We also welcome OEM and ODM orders. "Top Quality, Customer First" is our conviction, and we implement the principle of "high standards, safe & fast delivery, good service" to create a mutual benefit partnership with customers. We warmly welcome overseas customer to establish long-term cooperation.

Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder
Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Certifications

1. All of our ingredients meet strict quality and food safety standards, and surpass industry standards for purity and cleanliness.
2. Our food ingredients are certified to applicable organic standards: National Organic Program (NOP) and European Union (EU).
3. We use organic certificate who meet or exceed IFOAM standards and are accepted worldwide.
4. We also can provide ISO, HACCP, KOSHER certification.

Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

Pharmaceutical Intermediate Cosmetic Material API Isotretinoic Acid 99% CAS 4759-48-2 Isotretinoic Acid Powder

FAQ

Q1: How can I get a sample?
A: Free samples is available. You only pay shipping cost.

Q2: Which payment terms do you accept?
A: Payment can be done by T/T, Western Union,Money Gram,etc.

Q3: How to confirm the Product Quality before placing orders?
A: Every product is with professional COA. Please be sure about the quality.If any doubt, sample is available to you to be tested before large quantity order.

Q4: When will my order be shipped?
A: Within 3 working days after the payment.

Q5: How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,we will
send you free goods for replacement or refund your loss.

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