Antidepressant CAS No 138112-76-2 Agomelatine Powder

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, HSE, ISO 9001, USP, BP, ISO22000, Halal
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Model NO.: HZ- Agomelatine
• CAS No.: 138112-76-2
• Appearance: White Powder
• Test Method: HPLC
• Molecular Formula: C15h17no2
• Grade: Chemical
• Transport Package: Pharm Vail
• Specification: 10mg/vial, 1g/vial, 10vial/box
• Trademark: Customzied accepted
• Origin: China
• HS Code: 2924199090
• Production Capacity: 800 Boxes/Month

Product Description

Product Description

Agomelatine is an atypical antidepressant most commonly used to treat major depressive disorder and generalized anxiety disorder.One review found that it is as effective as other antidepressants with similar discontinuation rates overall but less discontinuations due to side effects.Another review also found it was similarly effective to many other antidepressants.
Common side effects include weight gain, fatigue, liver problems, nausea, headaches, and anxiety.Due to potential liver problems ongoing blood tests are recommended. Its use is not recommended in people with dementia or over the age of 75.There is tentative evidence that it may have fewer side effects than some other antidepressants.It acts by blocking certain serotonin receptors and activating melatonin receptors.

 

 

Function & Application

Function:

1.Major depressive disorder
Agomelatine is used for the treatment of major depressive episodes in adults in Europe.Ten placebo controlled trials have been performed to investigate the short term efficacy of agomelatine in major depressive disorder. At the end of treatment, significant efficacy was demonstrated in six of the ten short-term double-blind placebo-controlled studies.Two were considered "failed" trials, as comparators of established efficacy failed to differentiate from placebo. Efficacy was also observed in more severely depressed patients in all positive placebo-controlled studies.The maintenance of antidepressant efficacy was demonstrated in a relapse prevention study.
In 2018, a systematic review and network meta-analysis comparing the efficacy and acceptability of 21 antidepressant drugs showed agomelatine to be one of the most effective and one of only two medications found to be more tolerable than placebo.

2.Generalized anxiety disorder
Agomelatine has been found more effective than placebo in the treatment of generalized anxiety disorder in a number of short-term double-blind placebo-controlled studies and in long term relapse prevention.

3.Use in special populations
It is not recommended in Europe for use in children and adolescents below 18 years of age due to a lack of data on safety and efficacy.However, a recent 12 week study first reported in September 2020, and published in 2022 showed greater efficacy vs. placebo for agomelatine 25 mg per day in youth age 7-17 years and an acceptable tolerability profile with similar efficacy to fluoxetine.Only limited data is available on use in elderly people ≥ 75 years old with major depressive episodes.
It is not recommended during pregnancy or breastfeeding.

Packaging & Shipping

OEM service
As a supplier of plant extracts for 15 years, we can guarantee the quality of products, we can provide different customized services.If you have any requirements, please contact us.

1. Timely online communication and reply within 12 hours;

2. Choose high-quality raw materials;

3.OEM/ODM available;

4. Reasonable and competitive price;

5. Free samples can be provided;

6. Credit guarantee: Made in China third-party trade guarantee;

7. Fast delivery time: Stable inventory of products;Mass production within 7 days;

8. Quality assurance: Internationally authorized third party testing for the products you need.
 

If there is a product quality problem, if the test is unqualified, there is after-sales guarantee,we can return and exchange the product free of charge, so that you have no worries.

Our Advantages:
---We are very experienced with this field(more than 10 years);
---Good after-sales service
---100% quality guaranteed;
---We accept sample order for testing;
---Strong supply ability;
---Provide various customizations,
---Made in China gold members with high credit guarantee.

 

Our Advantages

 

FAQ

Q1: Could i start the order with small quantity ? 

A: We accept sample order , the more details please contact us to know about. 

Q2: Could you accept customzied order? 
A: Yes, we accept customized service according your inquire, you can communicate with sales manager to know more details.

Q3: When the product can be delivery? 
A: We normal delivery the product within 2-4 days, the more details will inform to you by our sales manager. 

Q4: Could i get certificate of analysis (COA) about product?
A: Of course, please contact us to get it.