What is Mebendazole ?
Mebendazole is a broad-spectrum deworming drug, which can completely kill the eggs of hookworm and whipworm and partially kill the eggs of ascaris. It has a strong affinity for the β-tubulin of the worm and can bind to it at very low concentrations. It can inhibit the polymerization of its microtubules by affecting the metabolism of sugars and related energy production of the worm, and cause the loss of the epidermis or intestinal cells of the worm. It can selectively and irreversibly inhibit the intake of glucose and other nutrients from the intestinal tract, and eventually lead to the death of the insect. It is suitable for the treatment of human and animal infections caused by whipworm, pinworm, hookworm, tapeworm, strongylus faecalis, roundworm and other single or multiple worms, but ineffective for hydatid disease.
Photo:
Details:
Product name |
Mebendazole |
Cas number |
31431-39-7 |
Apperance |
White Powder |
Density |
1.388 |
MF |
C16H13N3O3 |
Melting point |
288.5ºC |
MW |
295.29272 |
COA:
Item |
Specification |
Result |
Characteristic |
A white or almost white powder |
Almost white powder |
Solubility |
Practically insoluble in water,in alcohol and in methylene cde, It shows polymorphism |
conforms |
Infrared Absorption |
Comform to the spectrum obtained from Mebendazole RS |
conforms |
Related substances |
Impurity G not more than 0.5% Any other individual impurity not more than 0.25% Total impurities not more than 1.0% |
<0.05% <0.05% <0.05% |
Loss on drying |
Not more than 0.5% |
0.06% |
Residue on ignition |
Not more than 0.1% |
0.06% |
Partical size distribution |
Particals smaller than 20um should be no less than 90% |
conforms |
Assay |
It contains not less than 99.0% and not more than 101.0% of C16H13N3O3 calculated on the dried basis |
99.8% |
Conclusion |
The quality of the above commodity complies with the standard of BP2008 and in-house specification. |
Funcation:
Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm,
hookworm, whipworm, threadworm, pinworm, and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract. Other drugs are used to treat worm infections outside the digestive tract, as mebendazole is poorly absorbed into the bloodstream. Mebendazole is used alone in those with mild to moderate infestations. It kills parasites relatively slowly, and in those with very heavy infestations, it can cause some parasites to migrate out of the digestive system, leading to appendicitis, bile duct problems, or intestinal perforation. To avoid this, heavily infested patients may be treated with piperaze, either before or instead of mebendazole. Pipezine paralyses the parasites, causing them to pass in the feces. It is also used rarely in the treatment of hydatid disease. Evidence for effectiveness for this disease
Goods weight
|
Packing
|
Shipping method
|
Lead-time
|
1-50kg
|
Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum
|
International express
|
1~3 days after your payment |
100-200kg
|
25kg/drum,use two layer PP bag,then into cardboard drum
|
Air shipping
Sea Shipping |
3~5 days after your payment |
Over 500kg
|
25kg/drum,use two layer PP bag,then into cardboard drum
|
Sea shipping
|
5~10 days after your payment |
Q1: Can I get some free sample?
A: Yes, we offer free sample to client and you only need to pay the fright.
Q2: Could you accept customzied order?
A: Yes, we accept customized service according your requests, you can communicate with sales manager to know more details.
Q3: When the product can be delivery?
A: We normal delivery the product within 2-4 days, the more details will inform to you by our sales manager.
Q4: Could i get certificate of analysis (COA) about product?
A: Of course, please contact us to get it.
Q5: Is there any discount?
A:Yes, we can give you discount, but it depends on your quantity.