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As an important component of bile, bile acid is synthesized by cholesterol in the liver and stored in gallbladder. After ingesting food, as the bile flows into the duodenum, promote intestinal lipid absorption, and through passive diffusion and active transportation, transport and absorb at the end of the iconic end, and return to the liver through the door vein. Intestinal liver circulation. In -depth research on bile acid in recent years has found that bile acid is not only an emulsifier, but it can also be used as an important signal transmission molecule to regulate the metabolism of the host and affect the metabolism of sugar fat and energy steady.
Function
1. Bile acid provides an important excretion for cholesterol metabolism. The decomposition metabolism of three -point cholesterol is achieved by bile acid synthesis.
2. The absorbed bile acid has a negative feedback regulating effect on the bile acid synthesis, so it also plays a negative feedback regulating effect on the decomposition of cholesterol.
3. Bile acid can promote the secretion of cholesterol in bile, and it plays an important role in maintaining the solubility of cholesterol.
4. Bile acid can be absorbed by intestinal cholesterol.
5. The regulation of cholesterol synthesis in the liver is closely related to the intestinal and liver circulation of bile acid.
6. Bile acid can regulate intestinal cholesterol synthesis.
Bile acid helps to emulsify the fat, enhances the lipid solution of the pancreas, and promotes the absorption of lipid substances in the intestine by forming a hybrid glue to improve the solubility of lipids. The important role of bile acid on fat absorption by fat is confirmed by fats and symptoms of intestinal bile salt concentration such as bile salt concentration, such as bile gurgas, liver cirrhosis, and bile acid binding drugs.
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