Wholesale Pharmaceutical Intermediate 99% Purity Mildronate Powder CAS 76144-81-5

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Model NO.: HZ- Mildronate
• Grade: Healethcare Products
• CAS No.: 76144-81-5
• Appearance: White Crystal Powder
• Molecular Formula: C6h14n2o2
• Assay: 99%
• Test Method: HPLC
• Molrcular Weight: 554.73
• Shelf Life: 2 Years
• OEM: Customization Label and Packing Bottles
• Transport Package: Bottle and Carton
• Specification: 500mg/capsule
• Trademark: Customzied
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

Product Description

Mildronate(also known as THP, MET-88 and mildronate) is a novel cardioprotective agent.

Mildronateacts on mitochondria at the cellular level to improve myocardial energy metabolism. In view of these drugs and other anti-myocardial ischemia significantly different, also known as cell anti-ischemic drugs.

Mildronate is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation. Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.

 

Product Specificaiton

Product Name	Mildronate	Assay:	99%
Standard	Enterprise standard	Appearance:	White Crystalline Powder
CAS NO	76144-81-5	EINECS	682-135-0
Minimum  order  quantity	500g	Packing:	1kg/aluminum foil bag; 25kg/drum

ITEM	STANDARD	RESULTS
Appearance	White or almost white crystalline powder	White crystalline powder
Dissolution	Easily solubale in water, solubale in 95% alcohol	Complies
Indentification	(1) Should be positive respond (2) IR graphs should be conforms to the reference standard	Complies
pH	7.0~9.0	7.94
Clarity	should be not more than 1# working standard solution	Complies
Color	Should be lighter than the standard solution	Complies
Optical transmission	Not less than 95%	99.2%
Water	19.0~21.0%	19.66%
Chlorides	Not more than 0.01%	Complies

 

Function & Application

Function:
1. Mildronate powder is a novel cardioprotective agent.
2.Mildronate acts on mitochondria at the cellular level to improve myocardial energy metabolism. In view of these drugs and other anti-myocardial ischemia significantly different, also known as cell anti-ischemic drugs.
3. Mildronate is a structural analog of carnitine that competes in the inhibition of butyrate betaine hydroxylase, thereby inhibiting the biosynthesis of carnitine, which directly inhibits the transport of carnitine-dependent fatty acids in mitochondria. Inhibition of carnitine biosynthesis can reduce the concentration of intracellular free carnitine and prevent isoproterenol-induced acyl carnitine accumulation.

Therefore, the drug has a significant protective effect on the myocardium, resulting in this protective effect at the same time on the hemodynamic parameters had no significant effect, cardiac blood supply and cardiac oxygen consumption was no significant change.
Application:
1.Cardiovascular disease - stable angina, chronic heart failure, cardiomyopathy, functional cardiovascular system failure;
2.Acute and chronic ischemic attacks;
3.The ability to work under high physical and psychological load decreases;
4.Recovery from cerebrovascular disease, brain injury, and encephalitis.
5.Alcohol withdrawal symptoms.

OEM Service

As a professional health product supplier, we can customize Mildronate powder with different packing, Mildronate capusel with different bottles according to your formula and requests.

                                                                                                                               
 

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Packaging & Shipping

Goods weight	Packing	Shipping method	Lead-time
1-50kg	Below 5kg Use Foil bag;5-25kg use two layer PP bag,then into master carton or cardboard drum	International express	1~3 days after your payment
100-200kg	25kg/drum,use two layer PP bag,then into cardboard drum	Air shipping Sea Shipping	3~5 days after your payment
Over 500kg	25kg/drum,use two layer PP bag,then into cardboard drum	Sea shipping	5~10 days after your payment

 

Company Profile

FAQ

Q1: Can I get some free sample?

A: Yes, we offer free sample to client and you only need to pay the fright.

Q2: Could you accept customzied order? 
A: Yes, we accept customized service according your requests, you can communicate with sales manager to know more details.

Q3: When the product can be delivery? 
A: We normal delivery the product within 2-4 days, the more details will inform to you by our sales manager. 

Q4: Could i get certificate of analysis (COA) about product?
A: Of course, please contact us to get it. 
 

Q5: Is there any discount?

A:Yes, we can give you discount, but it depends on your quantity.