Alpha GPC/L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) /Choline Alfoscerate/ is a naturalcholine compound found in milk. L-Alpha glycerylphosphorylcholine (alpha-GPC, choline alfoscerate) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor .Alpha-GPC rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of acetylcholine.
Synonym
2-[[(2R)-2,3-dihydroxypropoxy]-hydroxy-phosphoryl]oxyethyl-trimethyl-azanium;L-A-GLYCEROPHOSPHORYLCHOLINEFROM*EGGYOLKFREEFORM;L-A-GLYCEROPHOSPHORYLCHOLINEFROMSOYBEAN,ChemicalbookFREEFORM;L-α-GLYCERYLPHOSPHORYLCHOLINE(GPC);,hydroxide,innersalt,(r)-;L-a-Glycerophosphorylcholine(anhydrous)(GPC);L-α-Glycerophosphorylcholine;GLYCERYLPHOSPHOCHOLINE
Product Name: |
Alpha GPC |
CAS NO.: |
28319-77-9 |
Othere Name: |
Choline glycerophosphate |
EINECS: |
248-962-2 |
Function: |
It plays an important role in the brain and nervous system |
Application: |
Pharmaceutical Intermediates |
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Functions of Alpha GPC
Alpha GPC is an intermediate of phospholipid metabolism that occurs naturally in the human body. It exists in cells and throughout the human body. It is structurally composed of choline, glycerol. It is a major preserved form of choline and is recognized as Source of Choline. Because it is an endogenous substance, its toxic and side effects are extremely low. After absorption, choline alfoscerate is decomposed into choline and glycerophospholipid under the action of enzymes in the body: choline participates in the Chemicalbook biosynthesis of acetylcholine, acetylcholine is a type of neurotriggering transmitter; glycerophospholipid is the precursor of lecithin. , involved in the synthesis of lecithin. The main pharmacological effects include protecting the metabolism of choline, ensuring the synthesis of acetylcholine and lecithin in the nerve membrane, improving blood circulation, and improving cognitive and behavioral responses for patients with brain capillary nerve injuries. In this field, no better new drugs have been launched or developed.
Application
Glycerophosphocholine is not only one of the main permeates of renal medullary cells, but can also change the concentration of permeates inside and outside cells in parallel. This is beneficial for cerebrovascular health and especially for behavioral and emotional disorders caused by brain decline. Glycerylphosphocholine has the potential ability to chemically treat and prevent a variety of biochemical lesions. Researchers found that it can change the structure of phosphate lipid compounds in neuronal membranes, and found that it has a unique effect in relieving physical tension among factors related to the syndrome of neurological tissue decline.
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